This Jarvik-7 artificial heart was used in the first bridge operation in 1985 meant to replace a failing heart while the patient waited for a donor organ.
In June, a team of surgeons at Duke University Hospital implanted the latest model of an artificial heart in a 39-year-old man with severe heart failure, a condition in which the heart doesn't pump properly. The man's mechanical heart, made by French company Carmat, is a new generation artificial heart and the first of its kind to be transplanted in the United States. It connects to a portable external power supply and is designed to keep the patient alive until a replacement organ becomes available.
Many patients die while waiting for a heart transplant, but artificial hearts can bridge the gap. Though not a permanent solution for heart failure, artificial hearts have saved countless lives since their first implantation in 1982.
What might surprise you is that the origin of the artificial heart dates back decades before, when an inventive television actor teamed up with a famous doctor to design and patent the first such device.
A man of many talents
Paul Winchell was an entertainer in the 1950s and 60s, rising to fame as a ventriloquist and guest-starring as an actor on programs like "The Ed Sullivan Show" and "Perry Mason." When children's animation boomed in the 1960s, Winchell made a name for himself as a voice actor on shows like "The Smurfs," "Winnie the Pooh," and "The Jetsons." He eventually became famous for originating the voices of Tigger from "Winnie the Pooh" and Gargamel from "The Smurfs," among many others.
But Winchell wasn't just an entertainer: He also had a quiet passion for science and medicine. Between television gigs, Winchell busied himself working as a medical hypnotist and acupuncturist, treating the same Hollywood stars he performed alongside. When he wasn't doing that, Winchell threw himself into engineering and design, building not only the ventriloquism dummies he used on his television appearances but a host of products he'd dreamed up himself. Winchell spent hours tinkering with his own inventions, such as a set of battery-powered gloves and something called a "flameless lighter." Over the course of his life, Winchell designed and patented more than 30 of these products – mostly novelties, but also serious medical devices, such as a portable blood plasma defroster.
| Ventriloquist Paul Winchell with Jerry Mahoney, his dummy, in 1951 |
A meeting of the minds
In the early 1950s, Winchell appeared on a variety show called the "Arthur Murray Dance Party" and faced off in a dance competition with the legendary Ricardo Montalban (Winchell won). At a cast party for the show later that same night, Winchell met Dr. Henry Heimlich – the same doctor who would later become famous for inventing the Heimlich maneuver, who was married to Murray's daughter. The two hit it off immediately, bonding over their shared interest in medicine. Before long, Heimlich invited Winchell to come observe him in the operating room at the hospital where he worked. Winchell jumped at the opportunity, and not long after he became a frequent guest in Heimlich's surgical theatre, fascinated by the mechanics of the human body.
One day while Winchell was observing at the hospital, he witnessed a patient die on the operating table after undergoing open-heart surgery. He was suddenly struck with an idea: If there was some way doctors could keep blood pumping temporarily throughout the body during surgery, patients who underwent risky operations like open-heart surgery might have a better chance of survival. Winchell rushed to Heimlich with the idea – and Heimlich agreed to advise Winchell and look over any design drafts he came up with. So Winchell went to work.
Winchell's heart
As it turned out, building ventriloquism dummies wasn't that different from building an artificial heart, Winchell noted later in his autobiography – the shifting valves and chambers of the mechanical heart were similar to the moving eyes and opening mouths of his puppets. After each design, Winchell would go back to Heimlich and the two would confer, making adjustments along the way to.
By 1956, Winchell had perfected his design: The "heart" consisted of a bag that could be placed inside the human body, connected to a battery-powered motor outside of the body. The motor enabled the bag to pump blood throughout the body, similar to a real human heart. Winchell received a patent for the design in 1963.
At the time, Winchell never quite got the credit he deserved. Years later, researchers at the University of Utah, working on their own artificial heart, came across Winchell's patent and got in touch with Winchell to compare notes. Winchell ended up donating his patent to the team, which included Dr. Richard Jarvik. Jarvik expanded on Winchell's design and created the Jarvik-7 – the world's first artificial heart to be successfully implanted in a human being in 1982.
The Jarvik-7 has since been replaced with newer, more efficient models made up of different synthetic materials, allowing patients to live for longer stretches without the heart clogging or breaking down. With each new generation of hearts, heart failure patients have been able to live relatively normal lives for longer periods of time and with fewer complications than before – and it never would have been possible without the unsung genius of a puppeteer and his love of science.
Dry, arid and remote farming regions are vulnerable to water shortages, but scientists are working on a promising new solution.
As scientists have searched for solutions, an alternative water supply has been hiding in plain sight: Water vapor in the atmosphere. It is abundant, available, and endlessly renewable, just waiting for the moment that technological innovation and necessity converged to make it fit for use. Now, new super-moisture-absorbent gels developed by Yu and a team of researchers can pull that moisture from the air and bring it into soil, potentially expanding the map of farmable land around the globe to dry and remote regions that suffer from water shortages.
"This opens up opportunities to turn those previously poor-quality or inhospitable lands to become useable and without need of centralized water and power supplies," Yu said.
A renewable source of freshwater
The hydrogels are a gelatin-like substance made from synthetic materials. The gels activate in cooler, humid overnight periods and draw water from the air. During a four-week experiment, Yu's team observed that soil with these gels provided enough water to support seed germination and plant growth without an additional liquid water supply. And the soil was able to maintain the moist environment for more than a month, according to Yu.
The super absorbent gels developed at the University of Texas at Austin.
Xingyi Zhou, UT Austin
"It is promising to liberate underdeveloped and drought areas from the long-distance water and power supplies for agricultural production," Yu said.
Crops also rely on fertilizer to maintain soil fertility and increase the production yield, but it is easily lost through leaching. Runoff increases agricultural costs and contributes to environmental pollution. The interaction between the gels and agrochemicals offer slow and controlled fertilizer release to maintain the balance between the root of the plant and the soil.
The possibilities are endless
Harvesting atmospheric water is exciting on multiple fronts. The super-moisture-absorbent gel can also be used for passively cooling solar panels. Solar radiation is the magic behind the process. Overnight, as temperatures cool, the gels absorb water hanging in the atmosphere. The moisture is stored inside the gels until the thermometer rises. Heat from the sun serves as the faucet that turns the gels on so they can release the stored water and cool down the panels. Effective cooling of the solar panels is important for sustainable long-term power generation.
In addition to agricultural uses and cooling for energy devices, atmospheric water harvesting technologies could even reach people's homes.
"They could be developed to enable easy access to drinking water through individual systems for household usage," Yu said.
Next steps
Yu and the team are now focused on affordability and developing practical applications for use. The goal is to optimize the gel materials to achieve higher levels of water uptake from the atmosphere.
"We are exploring different kinds of polymers and solar absorbers while exploring low-cost raw materials for production," Yu said.
The ability to transform atmospheric water vapor into a cheap and plentiful water source would be a game-changer. One day in the not-too-distant future, if climate change intensifies and droughts worsen, this innovation may become vital to our very survival.
