longevity

Scientists Are Studying How to Help Dogs Have Longer Lives, in a Bid to Further Our Own

Health Feature Story
Scientists Are Studying How to Help Dogs Have Longer Lives, in a Bid to Further Our Own

Feeding dogs only once a day is showing health benefits in a large study, scientists report.

Photo by Eric Ward on Unsplash

The sad eyes. The wagging tail. The frustrated whine. The excited bark. Dogs know how to get their owners to fork over the food more often.

The extra calories dogs get from feeding patterns now used by many Americans may not be good for them from a health and longevity viewpoint. In research from a large study called the Dog Aging Project, canines fed once a day had better scores on cognition tests and lower odds of developing diseases of organs throughout the body: intestinal tract, mouth and teeth, bones and joints, kidneys and bladder, and liver and pancreas.

Fewer than 1 in 10 dog owners fed their furry friends once daily, while nearly three fourths provided two daily meals.

“Most veterinarians have been led to believe that feeding dogs twice a day is optimal, but this is a relatively new idea that has developed over the past few decades with little supportive evidence from a health standpoint,” said Matt Kaeberlein, PhD, Co-Director of the Dog Aging Project, a professor of pathology and Director of the Healthy Aging and Longevity Research Institute at the University of Washington. Kaeberlein studies basic mechanisms of aging to find ways of extending the healthspan, the number of years of life lived free of disease. It’s not enough to extend the lifespan unless declines in biological function and risks of age-related diseases are also studied, he believes, hence the healthspan.

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L. Michael Posey
A pharmacist-editor-journalist since 1980, L. Michael Posey is a regular writer and editor for The Gerontological Society of America, Postgraduate Healthcare Education’s PowerPak.com website, and other clients. The author of several books and many news and journal articles, Posey is a founding editor of a landmark textbook in pharmacy, Pharmacotherapy: A Pathophysiologic Approach, a McGraw Hill title now in its 11th edition. He holds a master's degree in health and medical journalism and baccalaureate degrees in pharmacy and microbiology from the University of Georgia. Posey is the father of four sons and a daughter and resides in the Wine Country north of San Francisco. Follow him on Twitter @lmposey.
tech

A startup aims to make medicines in space

Health Environment & Space
A startup aims to make medicines in space

A company is looking to improve medicines by making them in the nearly weightless environment of space.

Adobe Stock

Story by Big Think

On June 12, a SpaceX Falcon 9 rocket deployed 72 small satellites for customers — including the world’s first space factory.

The challenge: In 2019, pharma giant Merck revealed that an experiment on the International Space Station had shown how to make its blockbuster cancer drug Keytruda more stable. That meant it could now be administered via a shot rather than through an IV infusion.

The key to the discovery was the fact that particles behave differently when freed from the force of gravity — seeing how its drug crystalized in microgravity helped Merck figure out how to tweak its manufacturing process on Earth to produce the more stable version.

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Kristin Houser
Kristin Houser is a staff writer at Freethink, where she covers science and tech. Her written work has appeared in Business Insider, NBC News, and the World Economic Forum’s Agenda, among other publications, and Stephen Colbert once talked about a piece on The Late Show, to her delight. Formerly, Kristin was a staff writer for Futurism and wrote several animated and live action web series.
genetics

Genes that protect health with Dr. Nir Barzilai

Podcast In The Lab
Genes that protect health with Dr. Nir Barzilai

Centenarians essentially won the genetic lottery, says Nir Barzilai of Albert Einstein College of Medicine. He is studying their genes to see how the rest of us can benefit from understanding how they work.

In today’s podcast episode, I talk with Nir Barzilai, a geroscientist, which means he studies the biology of aging. Barzilai directs the Institute for Aging Research at the Albert Einstein College of Medicine.

My first question for Dr. Barzilai was: why do we age? And is there anything to be done about it? His answers were encouraging. We can’t live forever, but we have some control over the process, as he argues in his book, Age Later.

Dr. Barzilai told me that centenarians differ from the rest of us because they have unique gene mutations that help them stay healthy longer. For most of us, the words “gene mutations” spell trouble - we associate these words with cancer or neurodegenerative diseases, but apparently not all mutations are bad.

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Lina Zeldovich

Lina Zeldovich has written about science, medicine and technology for Popular Science, Smithsonian, National Geographic, Scientific American, Reader’s Digest, the New York Times and other major national and international publications. A Columbia J-School alumna, she has won several awards for her stories, including the ASJA Crisis Coverage Award for Covid reporting, and has been a contributing editor at Nautilus Magazine. In 2021, Zeldovich released her first book, The Other Dark Matter, published by the University of Chicago Press, about the science and business of turning waste into wealth and health. You can find her on http://linazeldovich.com/ and @linazeldovich.