The Inside Story of Two Young Scientists Who Helped Make Moderna's Covid Vaccine Possible

The Inside Story of Two Young Scientists Who Helped Make Moderna's Covid Vaccine Possible

Scientists Jason Schrum and Kerry Benenato solved crucial challenges in mRNA vaccine development.

Photo credit: LinkedIn

In early 2020, Moderna Inc. was a barely-known biotechnology company with an unproven approach. It wanted to produce messenger RNA molecules to carry instructions into the body, teaching it to ward off disease. Experts doubted the Boston-based company would meet success.

Today, Moderna is a pharmaceutical power thanks to its success developing an effective Covid-19 vaccine. The company is worth $124 billion, more than giants including GlaxoSmithKline and Sanofi, and evidence has emerged that Moderna's shots are more protective than those produced by Pfizer-BioNTech and other vaccine makers. Pressure is building on the company to deliver more of its doses to people around the world, especially in poorer countries, and Moderna is working on vaccines against other pathogens, including Zika, influenza and cytomegalovirus.

But Moderna encountered such difficulties over the course of its eleven-year history that some executives worried it wouldn't survive. Two unlikely scientists helped save the company. Their breakthroughs paved the way for Moderna's Covid-19 shots but their work has never been publicized nor have their contributions been properly appreciated.

Keep ReadingKeep Reading
Gregory Zuckerman
Gregory Zuckerman is a Special Writer at the Wall Street Journal where he writes about business, economic, and investing topics. He's a three-time winner of the Gerald Loeb award, the highest honor in business journalism. Zuckerman regularly appears on such media outlets as CNBC, Fox, MSNBC, and is the author of A Shot to Save the World, The Greatest Trade Ever, The Frackers, and The Man Who Solved the Market.  
person using an apple watch
Luke Chesser - Unsplash

Today’s podcast guest is Rosalind Picard, a researcher, inventor named on over 100 patents, entrepreneur, author, professor and engineer. When it comes to the science related to endowing computer software with emotional intelligence, she wrote the book. It’s published by MIT Press and called Affective Computing.

Dr. Picard is founder and director of the MIT Media Lab’s Affective Computing Research Group. Her research and engineering contributions have been recognized internationally. For example, she received the 2022 International Lombardy Prize for Computer Science Research, considered by many to be the Nobel prize in computer science.

Keep ReadingKeep Reading
Matt Fuchs
Matt Fuchs is the host of the Making Sense of Science podcast and served previously as the editor-in-chief of Leaps.org. He writes as a contributor to the Washington Post, and his articles have also appeared in the New York Times, WIRED, Nautilus Magazine, Fortune Magazine and TIME Magazine. Follow him @fuchswriter.
Hidden figures: Five black women that changed science forever

Dr. May Edward Chinn, Kizzmekia Corbett, PhD., and Alice Ball, among others, have been behind some of the most important scientific work of the last century.


Keep ReadingKeep Reading
Sarah Watts

Sarah Watts is a health and science writer based in Chicago.