A new method could help the smallest of medicines hit their targets

A new method could help the smallest of medicines hit their targets

Jacob Brenner and his partners at the University of Pennsylvania's Perelman School of Medicine are finding new ways to get nanomedicines to arrive at their targets.

Perelman School of Medicine, University of Pennsylvania

Its strength is in its lack of size.

Using materials on the minuscule scale of nanometers (billionths of a meter), nanomedicines have the ability to provide treatment more precise than any other form of medicine. Under optimal circumstances, they can target specific cells and perform feats like altering the expression of proteins in tumors so that the tumors shrink.

Another appealing concept about nanomedicine is that treatment on a nano-scale, which is smaller yet than individual cells, can greatly decrease exposure to parts of the body outside the target area, thereby mitigating side effects.

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Ray Cavanaugh
Ray Cavanaugh is a freelance writer from Massachusetts. He enjoys very long walks, stopping occasionally to indulge in his Kindle Paperwhite.
When doctors couldn’t stop her daughter’s seizures, this mom earned a PhD and found a treatment herself.

Savannah Salazar (left) and her mother, Tracy Dixon-Salazaar, who earned a PhD in neurobiology in the quest for a treatment of her daughter's seizure disorder.

LGS Foundation

Twenty-eight years ago, Tracy Dixon-Salazaar woke to the sound of her daughter, two-year-old Savannah, in the midst of a medical emergency.

“I entered [Savannah’s room] to see her tiny little body jerking about violently in her bed,” Tracy said in an interview. “I thought she was choking.” When she and her husband frantically called 911, the paramedic told them it was likely that Savannah had had a seizure—a term neither Tracy nor her husband had ever heard before.

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Sarah Watts

Sarah Watts is a health and science writer based in Chicago.

A robot cafe in Tokyo is making work possible for people with disabilities.

A robot server, controlled remotely by a disabled worker, delivers drinks to patrons at the DAWN cafe in Tokyo.

Photo courtesy of dawn2021.orylab.com.

A sleek, four-foot tall white robot glides across a cafe storefront in Tokyo’s Nihonbashi district, holding a two-tiered serving tray full of tea sandwiches and pastries. The cafe’s patrons smile and say thanks as they take the tray—but it’s not the robot they’re thanking. Instead, the patrons are talking to the person controlling the robot—a restaurant employee who operates the avatar from the comfort of their home.

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Sarah Watts

Sarah Watts is a health and science writer based in Chicago.