Youth Climate Activists Expand Their Focus and Collaborate to Get Out the Vote
This article is part of the magazine, "The Future of Science In America: The Election Issue," co-published by LeapsMag, the Aspen Institute Science & Society Program, and GOOD.
For youth climate activists, Earth Day 2020 was going to be epic. Fueled by the global climate strikes that drew millions of young people into streets around the world in 2019, the holiday's historic 50th anniversary held the promise of unprecedented participation and enthusiasm.
Then the pandemic hit. When the ability to hold large gatherings came to a screeching halt in March, just a handful of weeks before Earth Day, events and marches were cancelled. Activists rallied as best they could and managed to pull off an impressive three-day livestream event online, but like everything we've experienced since COVID-19 arrived, it wasn't the same.
Add on climate-focused candidate Bernie Sanders dropping out of the U.S. presidential race in April, and the spring of 2020 was a tough time for youth climate activists. "We just really felt like there was this energy sucked out of the movement," says Katie Eder, 19-year-old founder and Executive Director of Future Coalition. "And there was a lot of cynicism around the election."
Isha Clarke, 17-year-old cofounder of Oakland's Youth vs. Apocalypse, says she was "upset" and "depressed" the following month in the wake of George Floyd's murder. "It was like, I'm already here, stuck inside because of COVID," she recalls, "which is already disproportionately killing Black people and Indigenous people. And it's putting people out of work and making frontline communities even more vulnerable. And I'm missing my senior year, and everything is just crazy—and then this."
Isha Clarke
Clarke started doing some organizing around Black Lives Matter, which led her to consider the weight of this moment. "I was thinking about strategy and tactics, and I was thinking 'What is going to make this a pivotal moment in history, rather than just a memorable one?' And I think what is going to make this a pivotal moment is this real understanding and organizing around true intersectionality, on really finding the points on which our struggles intersect, and tear down this foundational system that is the root cause of all of these things."
Eder also says that the Black Lives Matter movement helped re-energize and re-focus the youth climate movement. "It sort returned this energy to young people that said, 'Okay, we don't need a presidential candidate to be the person driving this revolution. This is a people's revolution, and so that's what we need to do. So over the course of the summer we saw the climate movement showing up for the Black Lives movement in a big way, with that really being the priority."
Intersectionality—the idea that things like climate justice and racial justice and economic justice are not separate spheres, but rather interconnected issues that need to be tackled together—has become a dominating theme of the youth climate movement. In Clarke's opinion, white supremacy, patriarchy, colonialism, and capitalism have led us to the climate crisis, and progress on the climate front must include addressing those issues.
"We know that to fix the problem we're going to need as many young people in the streets, voting, and in legislative offices as possible, and so far we've been able to work with pretty much anyone and everyone when there's overlap."
"Climate justice has to be about working to dismantle these systems of oppression in every way that they exist, whether that be through environmental racism or police brutality or our faulty education system or detention centers, or whatever that is," says Clarke. "There are so many ways in which these foundational systems of oppression are harming people."
Eder concurs. "I think we've known this all along, but it's heightened this year, that when we talk about climate justice, we have to talk about racial justice and social justice. That needs to be the leading theme. It's not just about the polar bears and the ice caps—it's about people. That's a people's problem, and that's what we need to keep coming back to, finding the humanity in the crisis that otherwise feels really abstract."
Now, with the election just weeks away, activists are focusing much of their energies on getting out the vote.
Saad Amer
Photo credit: Cassell Ferere
Saad Amer is the 26-year-old founder of Plus1Vote, an organization launched prior to the 2018 midterm elections that encourages voter registration and participation by asking everyone to bring one person with them to the polls. Amer, who holds a degree in Environmental Science and Public Policy from Harvard, has been an environmental activist since he was 13 and has traveled the world exploring different ways people and communities are trying to battle climate change.
"What I found was that there were just consistent barriers to actually accomplishing anything with regard to climate action," says Amer. "And what so much of it comes down to is our elected officials." He founded Plus1Vote to mobilize young adults to get out and vote with the logic that "young people could fundamentally swing the election in a direction of climate champions."
Plus1Vote doesn't just advocate for climate policy, though. It also folds the issues of gun violence, health care, voting rights, and social justice in its campaigns. Like the other activists we spoke to, intersectionality is key to Amer's approach to change—and voting in supportive elected officials is key to facilitating all of it.
"Whether you're a racial justice organization, whether you're a climate-focused organization, women's rights, whatever it is, there's a clear common denominator in how we can take action on every single one of those fronts," says Amer. That common denominator is voting.Saad Amer leads climate justice/racial justice march in the summer of 2019.
One quirk of youth activism is that many of the young people in the trenches aren't even old enough to vote themselves. Isha Clarke still has another year before she reaches voting age, but that isn't stopping her from pushing to get out the vote. In fact, her latest collaborative project is a campaign called "This is the Time," which launches in October and includes an action website where voting-age Americans can pledge to fight for the future and to vote for candidates who will too.
However, it would be a mistake to assume that all young climate change activists share the same political views—or even sit on the same side of the political aisle.
Benji Backer is a 22-year-old from Appleton, Wisconsin, who has been active in conservative politics since he was 10. Growing up in a family where "the environment was the number one value," Backer found himself frustrated with the political divide when it comes to the environment. So he decided to change it.
In 2017, he founded the American Conservative Coalition to make environmentalism bipartisan again, and to put forth market-based, limited-government ways to solve environmental challenges.
Backer says we need both sides at the table to solve the problem of climate change. He testified before Congress next to Greta Thunberg, and though they don't agree on everything, they shared the unified message that their generation was being left behind because of the unnecessary politicizing of climate change.
"Our generation doesn't look at the environment from a conservative vs. liberal angle," says Backer. "They look at it from an environmental angle. And to most young people, there's a deep frustration at the lack of action on a lot of issues, but most importantly climate change, because everyone knows it's a problem."
Backer believes that local, state, and federal governments have a role to play in solving climate change, but that role should be more about incentivising innovation in the marketplace than implementing hefty regulations. "The marketplace has spurred innovation and competition to create electric vehicles, to create better solar panels, to create wind energy," says Backer. "That's the marketplace doing it's thing." He points out that we don't have all the answers to solving climate change yet, and that we need to encourage innovation and technology in the marketplace to help us get there faster.
To show how companies are already playing a role in finding climate change solutions, Backer is currently on a 50-day tour of the country—in a Tesla—dubbed the "Electric Election Road Trip." His team is interviewing 40 companies, sharing their sustainability initiatives in a podcast, and compiling the experience into a documentary that will be released sometime next year.
Benji Backer gets a tour of Michigan University's Nuclear Lab
Credit: Keegan Rice.
Despite their different approaches to solutions, climate change activists across the political spectrum have found ways to work together. "We definitely collaborate on messaging," says Backer, "the importance of fighting climate change, the importance of youth action. And we know that to fix the problem we're going to need as many young people in the streets, voting, and in legislative offices as possible, and so far we've been able to work with pretty much anyone and everyone when there's overlap."
"And when there's not overlap," he adds, "we just go our separate ways for that specific issue."
There's no doubt that the pandemic and political upheaval we're all experiencing pose challenges to youth activists, but these young leaders are adjusting and charging ahead. The digital savvy they possess makes mobilizing and collaborating easier for them than for older generations, and they certainly aren't going to let a global virus outbreak stop them. The most striking thing about these young people is how their environmental knowledge, activism know-how, and ability to express themselves feels far beyond their years, without exception. While they're having to endure the uncertainty of the moment while navigating a pivotal stage of their own lives, these youth continue to provide a hopeful perspective and vision of the future—one that the world desperately needs.
[Editor's Note: To read other articles in this special magazine issue, visit the beautifully designed e-reader version.]
A new type of cancer therapy is shrinking deadly brain tumors with just one treatment
Few cancers are deadlier than glioblastomas—aggressive and lethal tumors that originate in the brain or spinal cord. Five years after diagnosis, less than five percent of glioblastoma patients are still alive—and more often, glioblastoma patients live just 14 months on average after receiving a diagnosis.
But an ongoing clinical trial at Mass General Cancer Center is giving new hope to glioblastoma patients and their families. The trial, called INCIPIENT, is meant to evaluate the effects of a special type of immune cell, called CAR-T cells, on patients with recurrent glioblastoma.
How CAR-T cell therapy works
CAR-T cell therapy is a type of cancer treatment called immunotherapy, where doctors modify a patient’s own immune system specifically to find and destroy cancer cells. In CAR-T cell therapy, doctors extract the patient’s T-cells, which are immune system cells that help fight off disease—particularly cancer. These T-cells are harvested from the patient and then genetically modified in a lab to produce proteins on their surface called chimeric antigen receptors (thus becoming CAR-T cells), which makes them able to bind to a specific protein on the patient’s cancer cells. Once modified, these CAR-T cells are grown in the lab for several weeks so that they can multiply into an army of millions. When enough cells have been grown, these super-charged T-cells are infused back into the patient where they can then seek out cancer cells, bind to them, and destroy them. CAR-T cell therapies have been approved by the US Food and Drug Administration (FDA) to treat certain types of lymphomas and leukemias, as well as multiple myeloma, but haven’t been approved to treat glioblastomas—yet.
CAR-T cell therapies don’t always work against solid tumors, such as glioblastomas. Because solid tumors contain different kinds of cancer cells, some cells can evade the immune system’s detection even after CAR-T cell therapy, according to a press release from Massachusetts General Hospital. For the INCIPIENT trial, researchers modified the CAR-T cells even further in hopes of making them more effective against solid tumors. These second-generation CAR-T cells (called CARv3-TEAM-E T cells) contain special antibodies that attack EFGR, a protein expressed in the majority of glioblastoma tumors. Unlike other CAR-T cell therapies, these particular CAR-T cells were designed to be directly injected into the patient’s brain.
The INCIPIENT trial results
The INCIPIENT trial involved three patients who were enrolled in the study between March and July 2023. All three patients—a 72-year-old man, a 74-year-old man, and a 57-year-old woman—were treated with chemo and radiation and enrolled in the trial with CAR-T cells after their glioblastoma tumors came back.
The results, which were published earlier this year in the New England Journal of Medicine (NEJM), were called “rapid” and “dramatic” by doctors involved in the trial. After just a single infusion of the CAR-T cells, each patient experienced a significant reduction in their tumor sizes. Just two days after receiving the infusion, the glioblastoma tumor of the 72-year-old man decreased by nearly twenty percent. Just two months later the tumor had shrunk by an astonishing 60 percent, and the change was maintained for more than six months. The most dramatic result was in the 57-year-old female patient, whose tumor shrank nearly completely after just one infusion of the CAR-T cells.
The results of the INCIPIENT trial were unexpected and astonishing—but unfortunately, they were also temporary. For all three patients, the tumors eventually began to grow back regardless of the CAR-T cell infusions. According to the press release from MGH, the medical team is now considering treating each patient with multiple infusions or prefacing each treatment with chemotherapy to prolong the response.
While there is still “more to do,” says co-author of the study neuro-oncologist Dr. Elizabeth Gerstner, the results are still promising. If nothing else, these second-generation CAR-T cell infusions may someday be able to give patients more time than traditional treatments would allow.
“These results are exciting but they are also just the beginning,” says Dr. Marcela Maus, a doctor and professor of medicine at Mass General who was involved in the clinical trial. “They tell us that we are on the right track in pursuing a therapy that has the potential to change the outlook for this intractable disease.”
Since the early 2000s, AI systems have eliminated more than 1.7 million jobs, and that number will only increase as AI improves. Some research estimates that by 2025, AI will eliminate more than 85 million jobs.
But for all the talk about job security, AI is also proving to be a powerful tool in healthcare—specifically, cancer detection. One recently published study has shown that, remarkably, artificial intelligence was able to detect 20 percent more cancers in imaging scans than radiologists alone.
Published in The Lancet Oncology, the study analyzed the scans of 80,000 Swedish women with a moderate hereditary risk of breast cancer who had undergone a mammogram between April 2021 and July 2022. Half of these scans were read by AI and then a radiologist to double-check the findings. The second group of scans was read by two researchers without the help of AI. (Currently, the standard of care across Europe is to have two radiologists analyze a scan before diagnosing a patient with breast cancer.)
The study showed that the AI group detected cancer in 6 out of every 1,000 scans, while the radiologists detected cancer in 5 per 1,000 scans. In other words, AI found 20 percent more cancers than the highly-trained radiologists.
Scientists have been using MRI images (like the ones pictured here) to train artificial intelligence to detect cancers earlier and with more accuracy. Here, MIT's AI system, MIRAI, looks for patterns in a patient's mammograms to detect breast cancer earlier than ever before. news.mit.edu
But even though the AI was better able to pinpoint cancer on an image, it doesn’t mean radiologists will soon be out of a job. Dr. Laura Heacock, a breast radiologist at NYU, said in an interview with CNN that radiologists do much more than simply screening mammograms, and that even well-trained technology can make errors. “These tools work best when paired with highly-trained radiologists who make the final call on your mammogram. Think of it as a tool like a stethoscope for a cardiologist.”
AI is still an emerging technology, but more and more doctors are using them to detect different cancers. For example, researchers at MIT have developed a program called MIRAI, which looks at patterns in patient mammograms across a series of scans and uses an algorithm to model a patient's risk of developing breast cancer over time. The program was "trained" with more than 200,000 breast imaging scans from Massachusetts General Hospital and has been tested on over 100,000 women in different hospitals across the world. According to MIT, MIRAI "has been shown to be more accurate in predicting the risk for developing breast cancer in the short term (over a 3-year period) compared to traditional tools." It has also been able to detect breast cancer up to five years before a patient receives a diagnosis.
The challenges for cancer-detecting AI tools now is not just accuracy. AI tools are also being challenged to perform consistently well across different ages, races, and breast density profiles, particularly given the increased risks that different women face. For example, Black women are 42 percent more likely than white women to die from breast cancer, despite having nearly the same rates of breast cancer as white women. Recently, an FDA-approved AI device for screening breast cancer has come under fire for wrongly detecting cancer in Black patients significantly more often than white patients.
As AI technology improves, radiologists will be able to accurately scan a more diverse set of patients at a larger volume than ever before, potentially saving more lives than ever.