COVID-19

Want to Motivate Vaccinations? Message Optimism, Not Doom

There is a lot to be optimistic about regarding the new safe and highly effective vaccines, which are moving society closer toward the goal of close human contact once again.

Photo by Christine Jou on Unsplash

After COVID-19 was declared a worldwide pandemic by the World Health Organization on March 11, 2020, life as we knew it altered dramatically and millions went into lockdown. Since then, most of the world has had to contend with masks, distancing, ventilation and cycles of lockdowns as surges flare up. Deaths from COVID-19 infection, along with economic and mental health effects from the shutdowns, have been devastating. The need for an ultimate solution -- safe and effective vaccines -- has been paramount.

On November 9, 2020 (just 8 months after the pandemic announcement), the press release for the first effective COVID-19 vaccine from Pfizer/BioNTech was issued, followed by positive announcements regarding the safety and efficacy of five other vaccines from Moderna, University of Oxford/AztraZeneca, Novavax, Johnson and Johnson and Sputnik V. The Moderna and Pfizer vaccines have earned emergency use authorization through the FDA in the United States and are being distributed. We -- after many long months -- are seeing control of the devastating COVID-19 pandemic glimmering into sight.

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Monica Gandhi
Monica Gandhi MD, MPH is a Professor of Medicine and Associate Chief in the Division of HIV, Infectious Diseases, and Global Medicine at the University of California, San Francisco (UCSF). She is also the Director of the UCSF Center for AIDS Research (CFAR) and the Medical Director of the HIV Clinic ("Ward 86") at San Francisco General Hospital. Her research focuses on HIV and women and adherence measurement in HIV treatment and prevention. She is now conducting research on mitigation strategies for COVID-19.
Inside Scoop: How a DARPA Scientist Helped Usher in a Game-Changing Covid Treatment

Amy Jenkins is a program manager for the Defense Advanced Research Projects Agency's Biological Technologies Office, which runs a project called the Pandemic Prevention Platform.

Photo credit: Neil Jenkins

Amy Jenkins was in her office at DARPA, a research and development agency within the Department of Defense, when she first heard about a respiratory illness plaguing the Chinese city of Wuhan. Because she's a program manager for DARPA's Biological Technologies Office, her colleagues started stopping by. "It's really unusual, isn't it?" they would say.

At the time, China had a few dozen cases of what we now call COVID-19. "We should maybe keep an eye on that," she thought.

Early in 2020, still just keeping watch, she was visiting researchers working on DARPA's Pandemic Prevention Platform (P3), a project to develop treatments for "any known or previously unknown infectious threat," within 60 days of its appearance. "We looked at each other and said, 'Should we be doing something?'" she says.

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Sarah Scoles
Sarah Scoles is a freelance science journalist based in Denver. She is a contributing writer at Wired, a contributing editor at Popular Science, and the author of the book Making Contact: Jill Tarter and the Search for Extraterrestrial Intelligence.
Everyone Should Hear My COVID Vaccine Experience

Dr. Ranney immediately after receiving her first dose of the Pfizer vaccine on December 18, 2020.

Credit: Bill Murphy, Lifespan

On December 18th, 2020, I received my first dose of the Pfizer mRNA vaccine against SARS-CoV-2. On January 9th, 2021, I received my second. I am now a CDC-card-carrying, fully vaccinated person.

The build-up to the first dose was momentous. I was scheduled for the first dose of the morning. Our vaccine clinic was abuzz with excitement and hope, and some media folks were there to capture the moment. A couple of fellow emergency physicians were in the same cohort of recipients as I; we exchanged virtual high-fives and took a picture of socially distanced hugs. It was, after all, the closest thing we'd had to a celebration in months.

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Megan L. Ranney
Dr. Megan L. Ranney is a practicing emergency physician, researcher, and advocate for innovative approaches to public health. She is Founding Director of the Brown-Lifespan Center for Digital Health, where her research focuses on using technology to improve adolescent mental health and reduce violence. She is also Chief Research Officer of AFFIRM Research, the country’s leading nonprofit committed to ending the gun violence epidemic through a non-partisan public health approach, and Co-Founder of GetUsPPE.org, a national nonprofit that gets donated personal protective equipment to healthcare workers in need. She is a Fellow of the fifth class of the Aspen Institute’s Health Innovators Fellowship Program.